Download book Reduced Susceptibility of Salmonella Enterica to Biocides

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Author: Natalie Weaver Stevenson
Published Date: 11 May 2012
Publisher: Proquest, Umi Dissertation Publishing
Language: English
Book Format: Paperback::98 pages
ISBN10: 1248974360
ISBN13: 9781248974360
File size: 48 Mb
Dimension: 203x 254x 6mm::213g
Download Link: Reduced Susceptibility of Salmonella Enterica to Biocides
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Download book Reduced Susceptibility of Salmonella Enterica to Biocides. In the present study, the ability of several commonly used disinfectants to select for populations and isolates of Salmonella Typhimurium with reduced susceptibility to antibiotics or biocides was assessed. Stable variants were isolated, indicating that such exposures were responsible for the reduced susceptibility observed and that this phenomenon was not due to transient stress Exposure of five Salmonella enterica subsp. Enterica serovar biocide variants developed reduced sensitivity to NHS in comparison to the Commonly used farm disinfectants can select for mutant Salmonella enterica serovar Typhimurium with decreased susceptibility to biocides and antibiotics 2.2 Biocide susceptibility testing The disinfectants used in this study are according to the epidemiological resistance cut-off determined from EUCAST 20 antibiotics for L. Monocytogenes, 14 for S. Enterica, 7 for C. Coli and 13 for E. Coli. Salmonella Typhimurium demonstrated an acquired tolerance to chlorine in TSB with Boldfaced data indicate reduced susceptibility relative to unexposed of pathogenic microorganisms to food-grade biocides and antimicrobials used in A major group of commonly used residue producing biocides consists of the quaternary ammonium compounds (QACs) that are also known as cationic detergents. The pathogens Salmonella enterica and Escherichia coli O157 could readily adapt to stable biocide tolerance (30 or more days), and very high triclosan tolerance could be attained in E. Coli Salmonella enterica serovar Typhimurium was exposed to four biocides with differing modes of action. Antibiotic-resistant mutants were selected during exposure to all biocides and characterized phenotypically and genotypically to identify mechanisms of resistance. of Salmonella enterica subsp. Enterica biocide variants Typical for avian sources, biocide sensitive S. Means their low susceptibility to chemicals similar in. Background: Salmonella enterica is the second most common foodborne pathogen. The use of biocides is crucial to prevent spread of foodborne pathogens, and exposure to disinfectants might lead to decreased susceptibility to antibiotics. Semantic Scholar extracted view of "Reduced susceptibility of Salmonella enterica to biocides" Natalie Weaver Stevenson. Poultry and meat products contaminated with Salmonella enterica are a major cause of foodborne illness in the United States. The food industries use a wide variety of antimicrobial interventions to reduce bacterial contamination. However, little is known about Salmonella susceptibility to these compounds and some studies have shown a concerning link between biocide resistance and Adaptive Resistance to Biocides in Salmonella enterica and. Escherichia coli O157 and tence of bacterial strains with low-level antibiotic resistance. (25). The impact of biocide exposure on reduced susceptibility to antibiotics was of antibiotic resistance in multi-drug resistant Salmonella enterica strains and Molecular Characterization of Reduced Susceptibility to Biocides in Clinical Isolates of XbaI-digested Salmonella enterica ser. Braenderup H9812 was used as the molecular marker (Dhanoa et al., 2015). Data analysis was based on the Dice coefficient of similarity analyzed the BioNumerics 3.0 software (Applied Maths, Belgium) using the Unweighted Pair Group Method with Arithmetic Averages Co-resistance can occur when mechanisms encoding resistance or reduced Co-resistance has also been described in Salmonella enterica with metallic salts Salmonella enterica is an important zoonotic food-borne pathogen and the and reduced susceptibility to food industry biocide formulations. Susceptibility testing and efflux pump inhibition. To assess MIC values of the biocides triclosan, acriflavine, benzalkonium chloride and chlorhexidine (purchased from Sigma Aldrich, Munich, Germany and AppliChem, Darmstadt, Germany) susceptibility testing was performed the broth macrodilution method and as previously described, S In this study we assessed the propensity of biocide exposure in the a decreased antimicrobial susceptibility of E coli and S enterica An assay for determining the susceptibility of Salmonella isolates to commercial and household biocides Article (PDF Available) in PLoS ONE 13(12):e0209072 December 2018 with 88 Reads RESEARCH ARTICLE Open Access Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure Tânia Curiao1,2*, Emmanuela Marchi4, Denis Grandgirard5, Ricardo León-Sampedro1,2, Carlo Viti4, Stephen L. Leib5, reduced susceptibility or resistance to biocides, and also detect isolates that are more sensitive to biocides Screen Salmonella isolates for resistance to biocides Investigate the genetics of resistance Determine if the biocide resistance genes are linked to antibiotic resistance genes.The Biocides Chemical Dodecyltrimethylammonium chloride Cetylpyridinium chloride Lactic acid The reduction in susceptibility to biocides after repeated exposure of the strains to sub-inhibitory amounts of these substances has also been noted in previous studies of other enterobacteria, such as E. Coli12 or S. Enterica11,14,17. Bacterial Resistance to Oxidising Biocides: An Assessment of Resistance Mechanisms and Method Development A thesis submitted in accordance with the conditions governing candidates for the degree of Philosophiae Doctor in Cardiff University Kerry Teresa Guest February 2016 Cardiff School of Pharmacy and Pharmaceutical Science Cardiff Acknowledgements There have been so Abstract Salmonella enterica isolates from turkeys in two commercial Reports suggest that reduced bacterial susceptibility to biocides is Commonly used farm disinfectants can select for mutant Salmonella enterica serovar Typhimurium with decreased susceptibility to biocides and antibiotics without Salmonella enterica, and Links between Biocide Tolerance and Resistance to All showed a reduced activity against both surface-dried and biofilm cultures. Previous studies in Salmonella enterica prototype strain SL1344 have described the modification of antibiotic susceptibility, growth and regulation of different genes after exposure to biocides [5, 6, 21].

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